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Glossary of life science terms

Life science uses various terms and concepts to explain the functions and processes of living organisms. Use this glossary to understand any unfamiliar terminology you come across.

To help you navigate, the glossary terms have been separated based on the topic they fall under. If you are unsure, just hit CTRL+F to find the term you are looking for!

Structure and function of cells

The table outlines the definitions for key terms in Structure and function of cells.

Term Definition
active transport a transport process that requires energy in which molecules move from a region of lower concentration to an area of higher concentration
anaphase the stage of mitosis in which sister chromatids are pulled apart by spindle fibres to opposide sides of the cell
antiporter a type of carrier protein that transports two molecules across the cell membrane at a time, in opposite directions
binary fission the process by which a single parent reproduces to form offspring
cell cycle a series of events that a cell goes through as it grows and divides
cell membrane a flexible phospholipid bilayer with embedded proteins and other molecules; also known as the plasma membrane
cell theory the cell is the most basic unit of life, all living organisms are composed of one or more cells and all cells arise only from pre-existing cells
cell wall the rigid outer layer that provides structural support and protection for plant cells
cellular respiration the chemical process that converts glucose and oxygen into energy in the form of ATP for the cell to function
centrosome structures found near the cell nucleus that are important for cell division
chlorophyll the green pigment that captures light energy
chloroplast the organelle in which photosynthesis occurs
chromatin a complex made of DNA and proteins
cisternae stacked membrane structures that make up the Golgi apparatus
cristae the structures that the inner membrane of the mitochondria are folded into
cytokinesis the stage after mitosis in which the cell's cytoplasm divides to form two distinct daughter cells
cytoplasm the gel-like filling inside a cell
cytoskeleton a network of protein fibres that help organiste the contents of a cell
endoplasmic reticulum a network of membranes involved in protein and lipid synthesis; abbreviated to ER
eukaryotic cell a cell that has a well-defined nucleus and membrane-bound organelles
facilitated diffusion a passive transport process in which molecules move from an area of higher concentration to an area of lower concentration with the help of special proteins
fluid mosaic model states that the cell membrane is a dynamic, flexible, semi-permeable phospholipid bilayer with embedded proteins
G1 stage the stage of interphase in which the cell grows and carries out regular metabolic functions
G2 stage the stage of interphase in which the cell continues to grow and produce what it needs for mitosis
Golgi apparatus the organelle that modifies, sorts and packages proteins and lipids for transport
grana stacks of thylakoids
interphase the phase in which the cell grows and its genetic material is replicated
lumen channel
lysosome the organelle that contains digestive enzymes to break down excess or old cell parts, food particles and invading viruses or bacteria
matrix (in mitochondria) the space inside the cristae
metaphase the stage of mitosis in which the chromosomes align at the equator of the cell
mitochondria the powerhouse of the cell that produces energy in the form of ATP for the cell to function
mitosis the process by which a cell divides into two identical daughter cells
multicellular an organism consisting of multiple cells
nuclear envelope a double membrane that surrounds the nucleus
nucleolus a dense area within the nucleus where the ribosomal RNA is found
nucleoplasm the gel-like filling inside a nucleus
nucleus the control centre of the cell that houses the cell's genetic material
organelle a specialised structure in eukaryotic cells that performs a distinct function
photosynthesis the chemical process that converts carbon dioxide, water and energy from sunlight into oxygen and glucose
prokaryotic cell a cell that lacks a cell nucleus and membrane-bound organelles
prophase the stage of mitosis in which the chromosomes condense and the nuclear envelope begins to dissolve
rate of diffusion the amount of material that is transported over a specific amount of time
ribosome the organelle that reads instructions from the messenger RNA to assemble proteins
rough endoplasmic reticulum endoplasmic reticulum with ribosomes attached; involved in protein folding and modification
S stage the stage of interphase in which DNA replication occurs
simple diffusion a passive transport process in which molecules move from an area of higher concentration to an area of lower concentration
smooth endoplasmic reticulum endoplasmic reticulum with no ribosomes attached; involved in lipid synthesis and detoxification
stoma the gel-like fluid surrounding the grana
surface area the total area of the cell's outer membrane
surface area to volume ratio a measure that compares the size of a cell's surface to its volume
symporter a type of carrier protein that transports two molecules across the cell membrane at a time, in one direction
telophase the stage of mitosis in which the nuclear envelope reforms around the separated chromosomes and they recondense
thylakoid a membrane in the chloroplast
unicellular an organism consisting of a single cell
uniporter a type of carrier protein that transports one molecule across the cell membrane in one direction
vacuole a storage organelle that stores water, nutrients and waste products in animal cells, and nutrients and waste products in animal cells
vesicle a small compartment into which molecules can be packaged into for transport
volume the amount of space inside the cell

Molecular biology

The table outlines the definitions for key terms in Molecular biology.

Term Definition
5' capping a post-transcriptional modification that involves adding a cap to the 5' end of the mRNA
acetylation the process in which an acetyl group is added
active site the site on an enzyme in which the substrates bind
aminoacyl site the A site of the tRNA where the tRNA with the correct anticodon binds
anticodon a complementary codon to the sense codon
carbohydrate a macromolecule made up of simple sugar monomers
catalyst something that speeds up a chemical reaction
central dogma a fundamental theory in molecular biology that describes the flow of genetic material
centromere the region of a chromatid in which the short and long arm meet
chromatid the structure of a chromosome which has a short arm and a long arm
chromatin a fibre of coiled solenoids
chromosome a condensed structure formed from the packaging and coiling of DNA
codon a set of three nucleotides that corresponds to an amino acid
competitive inhibitor a molecule that binds to the active site of an enzyme and blocks its natural substrate from binding
complementary base pairing the tendency for adenine to pair with thymine, and cytosine to pair with guanine
condensation a reaction in which two molecules come together and react to form one new molecule and release one water molecule
conformational change a change in the 3D structure of a molecule
denaturation a permanent change in the enzyme's structure that causes it to lose its ability to catalyse reactions
deoxyribonucleic acid a nucleic acid that carries the genetic instructions for the cell
enzyme a protein that speeds up chemical reactions
exit site the E site of the tRNA where the tRNA breaks away from the amino acid
glycosylation the process in which a sugar molecule is added
histone packaging proteins that bind to DNA
inactive having low activity
induced fit model states that an enzyme's active site changes shape slightly to bind substrates
initiation factor a protein that helps the mRNA template bind to the ribosome
initiator tRNA the tRNA that recognises the start codon
lipid a hydrophobic macromolecule involved in energy storage
lock-and-key model states that an enzyme's active site is rigid and specifically matches the shape of its substrates
macromolecule a large, complex molecule that is essential for life
methylation the process in which a methyl group is added
monosaccharide a simple monomer of sugar
mRNA messenger RNA that acts as a template for protein production
non-competitive inhibitor a molecule that binds to a different part of an enzyme and causes a conformational change that reduces it activity
nonsense codon a codon that does not correspond to an amino acid
nucleic acid a macromolecule that stores genetic information
nucleosome a section of DNA that is wrapped around a cluster of eight histones
nucleotide a simple monomer of nucleic acids; composed of a nitrogenous base, sugar and phosphate group
peptide bond the bond that links amino acids
peptidyl site the P site fo the tRNA where the amino acid forms a peptide bond with the previous amino acid in the peptide chain
peptidyl transferase an enzyme that helps join amino acids together
phosphodiester bond a bond that links nucleotides
phosphorylation the process in which a phosphate group is added
polyadenylation a post-transcriptional modification that involves adding a poly-A tail to the mRNA
pre-mRNA the product of transcription
primary structure the linear sequence of amino acids linked by peptide bonds
promoter region the region of the DNA that initiates transcription
protein a chain of amino acids
quaternary structure the arrangement of multiple protein subunits into a more complex structure
ribonucleic acid a nucleic acid that plays a role in translating DNA into proteins
RNA polymerase an enzyme that binds to a region of the DNA to start transcription
secondary structure the alpha helices or beta pleated sheets formed by hydrogen bonding between amino acid side chains
sense codon a codon that corresponds to an amino acid
solenoid a coiled spiral of nucleosomes
splicing a post-transcriptional modification that involves cutting introns out of the mRNA and rejoining exons together
start codon the codon AUG that corresponds to the amino acid methionine and also signals that start of translation
stop signal the region of the DNA that terminates transcription
substrate a molecule that binds to an enzyme
tertiary structure the overall 3D shape of a single protein molecule created by bonds between amino acid side chains
transcription the process in which a specific segment of DNA is copied into mRNA
translation the process in which an mRNA template is used to form a protein
tRNA transfer RNA that binds the mRNA template and reads it to form a protein
ubiquitination the process in which a ubiquitin molecule is added
uncompetitive inhibitor a molecule that binds to the enzyme–substrate complex and prevents the product from being released

Genetics

The table outlines the definitions for key terms in Genetics.

Term Definition
activator a regulatory protein that activates transcription
allele different version of a gene
autosomal dominant trait an autosomal trait that requires only one dominant allele for the trait to be expressed
autosomal recessive trait an autosomal trait that requires two copies of the recessive allele for the trait to be expressed
autosomal trait a genetic characteristic determined by genes located on the 22 pairs of autosomes
autosome a non-sex chromosome
carrier an individual that has the allele for the gene but does not express it
cell reproduction the division of cells to create new cells
constitutive gene a gene that is expressed at all times because it is continually being transcribed
cross breeding two organisms together to produce offspring
crossing over the process by which genetic material is exchanged between chromosomes; also called recombination
diploid a cell with two sets of chromosomes
DNA ligase an enzyme that joins together Okazaki fragments
DNA replication the process by which a cell makes an exact copy of its DNA before cell divsiion
dominant trait a trait that will show if one copy of the dominant allele is present
enhancer a region of the DNA where activators bind to increase transcription levels of the gene
facultative gene a gene that is expressed only when it is needed
gamete sex cells like sperm and eggs
gene a sequence of DNA that code for a protein
gene expression the process by which genes are used to produce proteins
gene regulation the process of controlling when and how much of a gene is expressed
genome an organism's entire set of DNA
genotype the allele specific to an individual
haploid a cell with a single set of chromosomes
helicase an enzyme that unwinds the DNA double helix
heterozygous a genotype consisting of two different alleles
homozygous a genotype consisting of two identical alleles
housekeeping gene a type of constitutive gene that is expressed at stable levels
karyotype a visual representation of an organism's complete set of chromosomes
lagging strand the strand of DNA that points away from the replication fork during DNA replication
law of dominance states that when there are two alleles of a gene, one can be dominant and hide the other
law of independent assortment states that alleles for different traits are distributed to gametes independently of one another
law of segregation states that during the formation of gametes, the two alleles of each trait separate so that each gamete receives only one allele
leading strand the strand of DNA that points towards the replication fork during DNA replication
meiosis a type of cell division that produces sex cells
meiosis I the first round of division during meiosis to produce two diploid daughter cells
meiosis II the second round of division during meiosis to produce four haploid daughter cells
Mendel's laws the principles of inheritance developed by Gregor Mendel
Okazaki fragment a short segment of DNA that is replicated from the lagging strand/td>
pedigree a chart that shows how a trait is passed down generations
phenotype a physical trait
promotor a region of the DNA where RNA polymerase binds to start transcription
Punnett square a diagram used to predict the genetic outcomes of a cross
recessive trait a trait that will show only if two copies of the recessive allele are present
recombination the process by which genetic material is exchanged between chromosomes; also called crossing over
replication fork where two single strands of DNA are exposed during DNA replication
repressor a regulatory protein that blocks transcription
sex chromosome an X or Y chromosome
sex-linked trait a genetic characteristic determined by genes located on the sex chromosomes
silencer a region of the DNA where repressors bind to reduce transcription levels of the gene
X-linked dominant trait a sex-linked trait that is caused by dominant alleles on the X chromosome
X-linked recessive trait a sex-linked trait that is caused by recessive alleles on the X chromosome
Y-linked trait a sex-linked trait that is associated with genes on the Y chromosome